OBJECTIVES: To evaluate how guidance on water-intake impacts the degree of nocturia.METHODS: A total of 67 male patients were enrolled in the present study. Patients were asked to adjust their water and food intakes so that their 24-h urine production/bodyweight would be equal or lower than 30 mL/kg. One month after the treatment, the therapeutic gain from and adverse effects of fluid restriction were examined by comparing the pretreatment and post-treatment value of various parameters.RESULTS: Overall, 65 eligible patients were evaluated. In 44 patients (67%), the frequency of nocturia was improved to one or more times. The change in frequency of nocturia showed a positive correlation with the change in nocturnal urine volume. The change in nocturnal urine volume showed a positive correlation with the changes in 24-h urine production/bodyweight, 24-h drinking volume and daytime drinking volume. The changes in 24-h urine production/bodyweight and daytime drinking volume were independent factors influencing therapeutic effect. None of the participants reported any adverse event.CONCLUSIONS: In patients with a 24-h urine production/bodyweight equal or higher than 30 mL/kg, guidance on water intake might be considered effective and safe as a lifestyle therapy. Water restriction should be carried out not only in the evening, but also during daytime.
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机译：目的：评估饮水指导对夜尿程度的影响。方法：本研究共纳入67名男性患者。要求患者调整水和食物的摄入量，以使他们的24小时尿液产量/体重等于或低于30 mL / kg。治疗一个月后，通过比较各种参数的治疗前和治疗后值，检查了限液治疗的疗效和不良反应。结果：总共评估了65名合格患者。在44例患者（67％）中，夜尿症的频率提高了一倍或更多倍。夜尿次数的变化与夜间尿量的变化呈正相关。夜间尿量的变化与24小时尿量/体重，24小时饮水量和白天饮水量的变化呈正相关。 24小时尿量/体重和白天饮水量的变化是影响治疗效果的独立因素。结论：在24小时尿量/体重等于或高于30 mL / kg的患者中，饮水指导可以作为一种生活方式疗法有效且安全。不仅应在晚上限制饮水，而且白天也应限制饮水。
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